- Active Substance: 5-Amino-1-methylquinolinium
- Concentration: 10 mg per vial
- Pack Size: 1 vial
- Manufacturer: Generic Peptides
- Brand Name: 5-Amino 1MQ
- Synonyms: 5-A-1MQ, 5A1MQ
- Molecular Formula: C10H11N2
- Molecular Weight: ~159.21 g/mol
- Mechanism: NNMT Inhibitor, NAD+ Modulation
SKU: P4376
5-Amino 1MQ 10 mg – NNMT Inhibitor for NAD+ & Fat Metabolism Research
Product Information
5-Amino 1MQ (5-Amino-1-methylquinolinium) 10 mg is a NAD+ modulator compound designed for metabolic and anti-aging research. It functions as an NNMT inhibitor, allowing cells to conserve NAD+, a vital coenzyme involved in energy production and cellular repair. This 10 mg dosage format offers researchers a flexible option for controlled studies in both short-term and chronic experimental protocols. Its activity is linked to improvements in mitochondrial efficiency and fat metabolism. Researchers exploring calorie restriction mimetics or metabolic rejuvenation pathways commonly use 5-Amino 1MQ to investigate NAD+-driven mechanisms.
Product Description
5-Amino 1MQ is a small molecule that modulates energy regulation by inhibiting the NNMT enzyme. In preclinical studies, this pathway is associated with reduced adiposity, improved insulin sensitivity, and preservation of NAD+ pools. The 10 mg concentration allows precise dose calibration, especially useful for evaluating dose-response relationships. Supplied as a research-grade compound, it remains stable in its lyophilized form and is easy to reconstitute for experimental use. Its potential applications extend to fat loss, anti-aging, and metabolic health optimization models.
Mechanism of Action
5-Amino 1MQ targets NNMT (nicotinamide N-methyltransferase), which depletes NAD+ via methylation of nicotinamide. By inhibiting NNMT, the compound helps maintain intracellular NAD+ levels, enhancing mitochondrial output, activating sirtuins, and supporting cellular longevity pathways. This mechanism promotes improved energy regulation and reduced fat accumulation. NAD+ is a coenzyme essential for key processes like DNA repair, ATP production, and oxidative metabolism—making 5-Amino 1MQ a powerful agent in NAD+ restoration research. Its unique action differentiates it from stimulants and traditional fat-loss pathways.
Use Case
From an Anti-Aging Specialist's viewpoint, 5-Amino 1MQ 10 mg represents a breakthrough tool for studying age-related metabolic slowdown. With age, NAD+ levels decline, contributing to mitochondrial dysfunction, insulin resistance, and fat gain. By preserving NAD+ levels, this compound may support healthier aging, lean mass retention, and improved energy efficiency. It is especially relevant in experimental models exploring non-hormonal anti-aging interventions, mitochondrial rejuvenation, and fat metabolism restoration. For scientists studying sirtuin pathways or NAD+ precursors, 5-Amino 1MQ is an advanced research asset.
FAQ
What is 5-Amino 1MQ?
5-Amino 1MQ (5-Amino-1-methylquinolinium) is a small molecule compound being studied for its ability to support cellular NAD+ levels. It works as an NNMT inhibitor, which helps reduce NAD+ depletion—a key factor in aging, fat metabolism, and cellular energy regulation.
What does 5-Amino 1MQ do?
5-Amino 1MQ is shown to inhibit the NNMT enzyme, helping preserve NAD+ levels inside cells. This can lead to enhanced mitochondrial activity, increased fat oxidation, and improved metabolic efficiency—particularly in models of aging or obesity. It's of particular interest in anti-aging and fat loss research.
How much 5-Amino 1MQ to take?
5-Amino 1MQ is sold strictly for research use only and is not approved for human consumption. Therefore, there is no recommended dosage for human use. Research protocols vary based on the experimental design and model being used. Always follow institutional guidelines and handle only in certified laboratory environments.
Legal & Compliance
This product is intended strictly for laboratory and research use only. It is not approved for human consumption, diagnosis, or treatment. Only qualified researchers and institutions may purchase and handle this compound. Misuse or off-label application is prohibited and may violate applicable regulations and laws.