- Active Substance: Enkephalin
- Concentration: 20 mg per vial
- Pack Size: 1 vial
- Manufacturer: Generic Peptides
- Brand Name: MET5
- Synonyms: Methionine-Enkephalin, Met-Enkephalin
- Molecular Formula: C27H35N5O7S
- Molecular Weight: 573.66 g/mol
- Sequence: Tyr-Gly-Gly-Phe-Met
SKU: P2860
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Brief Product Summary
MET5 20 mg, manufactured by Generic Peptides, is a synthetic form of Methionine-Enkephalin, an endogenous opioid peptide, designed for neurological research. This high-purity compound targets opioid receptor mechanisms, making it a critical tool for clinical pharmacology studies on pain modulation and dosage optimization. Produced in the USA, it ensures consistency and quality for advanced scientific investigations.
As a naturally occurring pentapeptide, MET5 interacts with opioid receptors in the brain and spinal cord, offering a focused approach to studying neurological pathways without the broad effects of larger opioids. Clinical pharmacologists value its short half-life and receptor specificity for exploring dose-response relationships and opioid signaling. This product is strictly for research purposes and not for human consumption.
Mechanism of Action
MET5 binds primarily to mu-opioid receptors (MOR) and delta-opioid receptors (DOR) in the central nervous system, activating G-protein-coupled signaling pathways to inhibit adenylate cyclase and reduce cyclic AMP levels. This action modulates neurotransmitter release, particularly reducing pain signaling by inhibiting substance P in nociceptive pathways. Its opioid receptor agonism makes it ideal for studying neurological pain mechanisms.
The peptide's rapid metabolism and short duration of action—due to enzymatic cleavage by peptidases—allow precise control in experimental models, supporting detailed pharmacokinetic studies. Clinical pharmacologists use MET5 to investigate receptor affinity, tolerance development, and the therapeutic potential of opioid peptides in neurological contexts.
- Binds MOR and DOR to modulate pain signaling
- Inhibits adenylate cyclase via G-protein pathways
- Reduces neurotransmitter release in nociception
- Short half-life for dose-response analysis
Potential Research Applications
MET5 20 mg is a cornerstone for clinical pharmacologists studying neurological mechanisms and dosage optimization. Research focuses on its ability to modulate pain perception in preclinical models, offering insights into opioid receptor function and analgesic pathways. Its specificity makes it a candidate for dissecting the neurological effects of endogenous opioids.
Additional applications include studies of opioid tolerance and dependence, critical for understanding chronic pain management strategies. MET5 is also used to explore its role in neuroprotection and stress response modulation, leveraging its opioid receptor activity. This peptide's precision drives research into neurological pharmacology and pain relief.
- Pain modulation and opioid receptor studies
- Dosage optimization and tolerance research
- Neuroprotection and stress response experiments
- Analgesic pathway modeling
Key Features & Benefits
MET5 20 mg from Generic Peptides offers exceptional purity and specificity, essential for neurological research. Its high solubility and stability support a range of experimental setups, from in vitro receptor binding assays to in vivo pain studies. Made in the USA, it adheres to strict quality standards and provides rapid domestic shipping.
The peptide's targeted opioid receptor agonism provides a reliable model for studying neurological mechanisms and optimizing dosages. Its short duration and minimal off-target effects make it a preferred choice for labs investigating pain and opioid pharmacology. MET5 20 mg is designed to advance scientific precision in neurological studies.
- Purity >98% for reliable outcomes
- USA-sourced for quality and speed
- Stable and soluble for versatile use
- Optimized for neurological research
Product Specifications
MET5 20 mg is supplied as a lyophilized powder in a sterile vial, engineered for stability in research applications. Each batch undergoes HPLC and mass spectrometry testing, confirming purity exceeding 98%. Its molecular formula, C27H35N5O7S, and molecular weight of 573.66 g/mol ensure accurate dosing for neurological experiments.
Reconstitute with 1-2 mL of bacteriostatic water or saline for optimal solubility. Store at 2-8°C, protected from light and heat, to maintain its integrity. This product is intended solely for laboratory research by qualified professionals, not for human or therapeutic use.
- Form: Lyophilized powder
- Purity: >98% (HPLC verified)
- Solubility: Bacteriostatic water or saline
- Storage: 2-8°C, protected from light
Legal Disclaimer
For research use only. Not for human consumption. This product is intended solely for laboratory research by qualified professionals and is not approved for medical, therapeutic, or diagnostic use.
Frequently Asked Questions (FAQ)
What is MET5 used for in research?
MET5 is studied for its effects on opioid receptors, pain modulation, and neurological mechanisms in research settings. It is not intended for human use.
How should MET5 20 mg be stored?
Store the lyophilized powder at 2-8°C, away from light and moisture. Reconstituted solutions should be refrigerated and used promptly.
What happens if a human consumes this?
MET5 is strictly for research use only and not for human consumption. Its safety and efficacy in humans are unproven, and it is not approved for medical use.
Is MET5 20 mg legal to purchase in the USA?
Yes, it is legal for research purposes in the USA when sourced from a reputable supplier like Generic Peptides for lab use only.
How is the purity of MET5 ensured?
Each batch undergoes HPLC and mass spectrometry testing to confirm purity above 98%, ensuring reliability for neurological research.