- Active Substance: Menotropins
- Concentration: 75 IU per vial
- Pack Size: 1 vial
- Manufacturer: Generic Peptides
- Brand Name: HMG
- Synonyms: Human Menopausal Gonadotropin, Menotropin
- Molecular Formula: Complex glycoprotein (FSH and LH components)
- Molecular Weight: Variable (glycoprotein mixture)
- Sequence: N/A (mixture of FSH and LH)
SKU: P2851
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Brief Product Summary
HMG 75 IU, manufactured by Generic Peptides, is a high-purity preparation of menotropins, a blend of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), tailored for endocrinology research. This compound is widely used to study hormonal regulation and reproductive processes, offering a reliable tool for exploring gonadotropin effects. Sourced in the USA, it ensures quality and consistency for advanced scientific studies.
Derived from purified urinary glycoproteins, HMG mimics the natural hormonal signals that drive follicle development and ovulation in experimental models. Endocrinologists value its dual FSH and LH activity, which provides a comprehensive approach to investigating reproductive endocrinology and metabolic hormone balance. This product is strictly for research purposes and not intended for human consumption.
Mechanism of Action
HMG functions by delivering both FSH and LH activities, directly stimulating gonadal tissues in research models. FSH promotes follicular growth and steroidogenesis in ovarian cells, increasing estrogen production, while LH triggers ovulation and supports the corpus luteum's progesterone synthesis. This dual action mimics the pituitary's role in the hypothalamic-pituitary-gonadal (HPG) axis, making HMG a key tool for studying hormonal interplay.
In male models, HMG enhances spermatogenesis by stimulating Sertoli cells (via FSH) and testosterone production in Leydig cells (via LH). Its glycoprotein structure ensures bioactivity, though its complexity requires precise handling in experiments. Endocrinologists use HMG to explore dose-dependent hormonal responses and their metabolic impacts in controlled settings.
- Stimulates follicular growth via FSH activity
- Triggers ovulation and progesterone via LH
- Enhances spermatogenesis and testosterone in males
- Mimics HPG axis signaling
Potential Research Applications
HMG 75 IU is essential for endocrinologists studying hormonal regulation and reproductive metabolism. Research applications include modeling ovarian follicle development and ovulation in preclinical studies, providing insights into fertility and endocrine function. Its balanced FSH and LH effects make it ideal for dissecting gonadotropin-dependent processes in both female and male models.
Additional studies explore HMG's role in metabolic hormone balance, such as its influence on steroid hormone synthesis and feedback loops within the HPG axis. It's also used to investigate hormonal deficiencies and their metabolic consequences, offering a window into endocrine disorders. This peptide's versatility supports cutting-edge research into reproductive and metabolic health.
- Ovarian follicle and ovulation studies
- Spermatogenesis and testosterone research
- HPG axis feedback and hormone balance experiments
- Endocrine disorder modeling
Key Features & Benefits
HMG 75 IU from Generic Peptides offers exceptional purity and bioactivity, critical for precise endocrinology research. Its stable formulation ensures reliable FSH and LH activity across experimental conditions, from in vitro assays to in vivo hormonal studies. Produced in the USA, it meets stringent quality standards and provides rapid domestic shipping.
The peptide's dual gonadotropin action provides a robust model for studying reproductive hormones and their metabolic effects. Its consistency and potency make it a preferred choice for labs investigating endocrine regulation. HMG 75 IU is designed to advance scientific understanding of hormonal and metabolic pathways.
- High purity for accurate hormonal effects
- USA-made for quality and reliability
- Stable formulation for versatile use
- Ideal for reproductive endocrinology research
Product Specifications
HMG 75 IU is supplied as a lyophilized powder in a sterile vial, optimized for stability in research applications. Each vial delivers 75 international units (IU) of menotropin activity, verified through bioassays and purity testing exceeding 98%. As a complex glycoprotein mixture, its composition includes FSH and LH components without a fixed molecular formula.
Reconstitute with 1-2 mL of bacteriostatic water or saline for optimal solubility. Store at 2-8°C, protected from light and heat, to preserve its bioactivity. This product is intended solely for laboratory research by qualified professionals, not for human or therapeutic use.
- Form: Lyophilized powder
- Purity: >98% (bioassay verified)
- Solubility: Bacteriostatic water or saline
- Storage: 2-8°C, protected from light
Legal Disclaimer
For research use only. Not for human consumption. This product is intended solely for laboratory research by qualified professionals and is not approved for medical, therapeutic, or diagnostic use.
Frequently Asked Questions (FAQ)
What is HMG used for in research?
HMG is studied for its effects on hormonal regulation, follicle development, and reproductive endocrinology. It is not intended for human use.
How should HMG 75 IU be stored?
Store the lyophilized powder at 2-8°C, away from light and moisture. Reconstituted solutions should be refrigerated and used promptly.
What happens if a human consumes this?
HMG is strictly for research use only and not for human consumption. Its safety and efficacy in humans are unproven outside controlled medical contexts, and it is not approved for personal use.
Is HMG 75 IU legal to purchase in the USA?
Yes, it is legal for research purposes in the USA when sourced from a reputable supplier like Generic Peptides for lab use only.
How is the purity of HMG ensured?
Each batch is tested via bioassays and purity analysis to confirm activity and purity above 98%, ensuring reliability for endocrine research.