Mod GRF (1-29) 10 mg | GH Research Peptide | USA Research Peptides

Brief Product Summary

Mod GRF (1-29) 10 mg (CJC-1295 no DAC), manufactured by Generic Peptides, is a synthetic analog of growth hormone-releasing hormone (GHRH) designed for GH research. This high-purity peptide stimulates pituitary GH secretion, making it a critical tool for clinical pharmacology studies on mechanisms and dosage optimization. Produced in the USA, it ensures reliability and quality for precise scientific investigations.

Unlike its DAC-containing counterpart, Mod GRF (1-29) has a shorter half-life, offering a pulsatile GH release profile ideal for studying natural secretion patterns. Clinical pharmacologists value its potency and specificity for exploring GHRH receptor interactions and dose-response relationships. This product is strictly for research purposes and not for human consumption.

Mechanism of Action

Mod GRF (1-29) binds to the GHRH receptor on pituitary somatotroph cells, activating adenylate cyclase and increasing cyclic AMP (cAMP) levels. This triggers a pulsatile release of growth hormone (GH) by mimicking the body's endogenous GHRH signaling, enhancing protein synthesis and cellular growth. Its short half-life—approximately 6-8 minutes—ensures rapid clearance, supporting studies of GH pulsatility.

The peptide's lack of Drug Affinity Complex (DAC) distinguishes it from longer-acting analogs, providing a transient yet potent GH spike. Clinical pharmacologists use Mod GRF (1-29) to investigate receptor affinity, GH secretion kinetics, and feedback inhibition by somatostatin, making it a prime candidate for dosage optimization research.

• Binds GHRH receptor to stimulate GH release
• Increases cAMP via adenylate cyclase activation
• Short half-life for pulsatile GH studies
• Supports protein synthesis and growth signaling

Potential Research Applications

Mod GRF (1-29) 10 mg is a key resource for clinical pharmacologists studying GH secretion mechanisms and dosage optimization. Research focuses on its ability to induce controlled GH pulses in preclinical models, offering insights into pituitary function and GH regulation. Its short-acting nature makes it ideal for exploring natural GH secretion dynamics.

Additional applications include studies of GH feedback loops and receptor desensitization, critical for optimizing administration protocols. Mod GRF (1-29) is also used to investigate GH's metabolic effects, such as IGF-1 production and energy regulation, in controlled settings. This peptide's precision drives research into GH-based therapeutic strategies.

• GH secretion and pituitary function studies
• Dosage optimization and receptor kinetics research
• GH feedback and IGF-1 production experiments
• Metabolic regulation modeling

Key Features & Benefits

Mod GRF (1-29) 10 mg from Generic Peptides offers exceptional purity and potency, vital for GH research. Its high solubility and stability support a range of experimental designs, from in vitro receptor assays to in vivo dosage studies. Made in the USA, it guarantees fast delivery and adherence to stringent quality controls.

The peptide's short-acting GH stimulation provides a reliable model for studying hormone mechanisms and optimizing dosages. Its specificity and rapid clearance enhance its utility in pharmacokinetic research. Mod GRF (1-29) 10 mg is engineered for labs advancing scientific precision in GH studies.

• Purity >98% for reliable outcomes
• USA-sourced for quality and speed
• Stable and soluble for versatile use
• Optimized for GH mechanism research

Product Specifications

Mod GRF (1-29) 10 mg is supplied as a lyophilized powder in a sterile vial, designed for stability in research applications. Each batch undergoes HPLC and mass spectrometry testing, confirming purity exceeding 98%. Its molecular formula, C₁₅₂H₂₅₂N₄₄O₄₂, and molecular weight of 3367.97 g/mol ensure accurate dosing for GH studies.

Reconstitute with 1-2 mL of bacteriostatic water or saline for optimal solubility. Store at 2-8°C, protected from light and heat, to maintain its integrity. This product is intended solely for laboratory research by qualified professionals, not for human or therapeutic use.

• Form: Lyophilized powder
• Purity: >98% (HPLC verified)
• Solubility: Bacteriostatic water or saline
• Storage: 2-8°C, protected from light

Legal Disclaimer

For research use only. Not for human consumption. This product is intended solely for laboratory research by qualified professionals and is not approved for medical, therapeutic, or diagnostic use.

Frequently Asked Questions (FAQ)